Most setups will require you to add your own SMTP or Outgoing Mail Server from your ISP (i.e. Comcast, SBCGlobal, Earthlink, etc). Please check with your provider for the correct mail server and settings.
Many providers require you to change the Outgoing Mail Server Port.
Outlook settings:
Mail Server Username: mailbox@yourdomain.com
OR
Mail Server Username: mailbox+yourdomain.com
Incoming Mail Server: mail.yourdomain.com
Outgoing Mail Server: (check with your ISP)
Supported Incoming Mail Protocols: POP3, POP3S (SSL/TLS), IMAP, IMAPS (SSL/TLS)
Supported Outgoing Mail Protocols: SMTP, SMTPS (SSL/TLS)
